Category: HIV/AIDS Research

The Arc of HIV History 4

Chapter IV: Solving The Riddle, A Consequential Approach

By AGT | May 23, 2021

The arc of HIV history has been developing over the last four decades.  In the early days there was much we did not know, but as teams of physicians, researchers and patients increased their understanding of the disease, progress was made.  Early efforts with repurposed cancer drugs gave way to numerous viral inhibitor combinations.  On a parallel course, attempts to… [Read More]

The Berlin Patient’s Success Produces A Flurry of Activity

By AGT | Dec 30, 2020

The Berlin Patient’s Success Produces A Flurry of Activity With an important milestone in the rearview mirror and clarity on the course ahead, the Berlin patient’s success invigorated new efforts to eliminate the CCR5 receptor.  Stem cell replacement cannot be practiced widely because of its risk, complexity and requirement for a highly compatible donor.  Many patients who received bone marrow… [Read More]

The History of HIV Cure Research: Reaching for a Cure

By AGT | Dec 8, 2020

Contributing Author: Gina Hagler A new immune deficiency illness came on the scene in 1981. In the years immediately following, four questions arose that indicated the uncertainty of the time: What was this illness? How was it transmitted? Could it be treated? Could it be cured? By 2004, when the number of people living with what we now knew as HIV… [Read More]

The History of HIV Cure Research: The Latest Research in BioPharma

By AGT | Dec 7, 2020

Contributing Author: Gina Hagler In the forty years since the HIV/AIDS pandemic began in 1981, researchers have learned a lot about this disease that destroys the immune system. Early on, they identified the method of transmission and the means of HIV replication. They went on to successfully turn what had been a deadly disease into a chronic illness through the daily… [Read More]

In Memory of Timothy Ray Brown

By AGT | Oct 2, 2020

A Message From the CEO of American Gene Technologies® Timothy Ray Brown – March 11, 1966 – September 29, 2020 Timothy Ray Brown was both a person and a turning point in the arc of HIV history. Timothy received a bone marrow transplant and became functionally cured; a symbol to the world that a cure for HIV was possible. He… [Read More]

4 Global Trends That Will Affect ​HIV Cure​ Research in 2025

By AGT | Oct 2, 2020

Contributing Author: Gina Hagler Researchers have been working on an HIV Cure since the first reports of the illness appeared in 1981. We now have effective treatment in the form of a cocktail of antiretroviral drugs that stop the HIV virus’s progression to full-blown AIDS, but It is not a cure. Despite their benefits, antiretrovirals bring a shortened lifespan and… [Read More]

The Arc of HIV History

By AGT | Sep 16, 2020

The Early Days When We Knew Nothing It is uncertain how the human immunodeficiency virus or HIV initially infected humans although there are educated guesses.  Research has suggested that the virus crossed species from chimpanzees to humans in Africa early in the 20th century.  Hunters would target chimpanzees or monkeys and consume their meat or become exposed to their blood,… [Read More]

The History of HIV Cure Research: Discovery to Treatment

By AGT | Sep 11, 2020

Contributing Author: Gina Hagler When reports of a new immune deficiency disease hit the news in the summer and fall of 1981, the cause and method of transmission were unknown. At first, it seemed this new disease only affected gay men and, as a result, what is now known as HIV/AIDS was viewed by many as the consequence of a gay lifestyle…. [Read More]

Gene and Cell Therapy Company Seeks To Cure HIV

Can HIV Be Cured? History of HIV Treatment Moving Toward an HIV Cure

By AGT | Dec 1, 2019

You don’t have to look far to find someone affected by HIV. It is estimated 1.1 million Americans are infected with the virus. The HIV virus has a storied history which we think began in the United States in 1968. Life might be easier if all things were black and white or had a root of 1. But, life almost… [Read More]

Can HIV Be Cured AGT Blog

Is HIV Curable?

By AGT | Dec 1, 2019

Is HIV Curable? American Gene Technologies® (AGT™) believes it is. Read why AGT’s Chief Science Officer is committed to discovering a cure for HIV during our lifetime. Written by: Dr. David Pauza Learn More In 1987, Robert Yarchoan and Samuel Broder provided a progress report (New England J. Med 316:557) on the initial efforts to develop antiretroviral therapy for HIV…. [Read More]

Second Patient Cured of HIV and The Implications for American Gene Technologies's AGT103-T

HIV Cure in the News

By AGT | Mar 5, 2019

Today the world celebrated the second patient cured of HIV. The work of Ravindra Gupta teaches us lessons not only of the potential for an HIV cure in the future, but how that cure may function. While a bone marrow transplant is not a practical way to cure HIV in most patients, the mechanism of action likely holds the key… [Read More]

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