American Gene Technologies: A Gene Therapy Biotech Company

Gene therapy is a technique that allows doctors to treat a disorder by inserting genes into patients’ cells to mitigate the underlying genetic drivers of disease. Human cells can be re-engineered to create highly-effective hunter/killers of invasive pathogens or cancer cells, or reprogramed to produce secretions that provide potent remedies to other disease conditions. There is strong evidence that this new therapeutic technology may unlock treatments and cures for formally untreatable or incurable human diseases, such as inherited genetic disorders, infectious diseases, and cancer.

Is the cure for cancer right around the corner?…

Advances in gene technologies and the resulting cures are accelerating exponentially while costs are coming down. If you were in Silicon Valley for the last 35 years, you’d recognize parallels to many previous high-tech “explosions” such as microcomputers, software and the Internet. “Moore’s Law” now applies to drug development and the next big startup could be up in a garage near you! Forget zeroes and ones… A-C-G-T is the new growth area of programming and real-world solutions. Viva la revolution!

Who We Are:

American Gene Technologies International Inc. (AGT) is a private biotechnology company developing cures and treatments for Infectious diseases, cancers and monogenic disorders. AGT uniquely:

Creates immunotherapy for HIV disease with gene modified T cells

Activates innate T cell immunity capable of killing all tumor cells with its vector used in immuno-oncology

Treats PKU by bringing a functional gene into cells that express a dysfunctional gene due to mutation

Moves its lentivirus vectors and gene therapies into the clinic today for diseases of high importance

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What We Do:

For over a decade, AGT has developed, tested and banked thousands of lentiviral vectors that can be adapted to the specific needs of new target diseases. AGT has developed gene therapy for diseases using this rapid gene delivery platform

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Gene Therapies

AGT’s platform allows it to pursue exciting clinical “cures” in large and orphan indications and complex diseases. The company has developed individual, intellectual property protected gene therapeutics that are breakthroughs in medicine.

GENE THERAPY

HIV/AIDS

Immunotherapy for HIV disease with gene modified T cells

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IMMUNO-ONCOLOGY

Liver Cancer

Activates innate T cell immunity capable of killing all tumor cells with its vector used in immuno-oncology

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GENE THERAPY

Phenylketonuria (PKU)

Treats PKU by bringing a functional gene into cells that express a dysfunctional gene due to mutation

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Pipeline

American Gene Technologies™ (AGT) is building a rich product pipeline based on its lentiviral vector platform. Our three leading therapeutics are well into the laboratory phase and scheduled to move into the clinical phase over the course of the next 6-18 months. AGT is in the process of testing and commercializing genetic medicines that will cure or halt the progression of several major diseases.

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Our Executive Team

Jeffrey A. Galvin

CEO and Founder

Jeff earned his BA degree in Economics from Harvard in 1981. He has more than 30 years of business and entrepreneurial experience including founder or executive positions at a variety of Silicon Valley startups.

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C. David Pauza, PhD

Chief Science Officer

David has held faculty positions over the last 35 years at University of Wisconsin and University of Maryland medical schools. Dr. Pauza is now an Adjunct Professor of Medicine at the University of Maryland Medical School.

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C. Neil Lyons, CPA

Chief Financial Officer & Executive Vice President

Neil has more than 30 years of experience in finance, strategy, raising capital, SEC compliance, and corporate governance in both public and private companies, with over 10 years of that leading finance for...

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Irene Tennant

Director, Clinical Development

Irene is the Director of Clinical Development for AGT. She brings more than 20 years of experience in clinical research and operations, and has lead teams in support of the development of biopharma products and pharmaceutical...

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