Chapter IV: Solving The Riddle, A Consequential Approach

Chapter IV: Solving The Riddle, A Consequential Approach

Contributing Author John Vandermosten, Senior Biotechnology Analyst The arc of HIV history has been developing over the last four decades.  In the early days there was much we did not know, but as teams of physicians, researchers and patients increased their understanding of the disease, progress was made.  Early efforts with repurposed cancer drugs gave way…

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5 Biotech Companies in Maryland That May Make History in 2021

5 Biotech Companies in Maryland That May Make History in 2021

Contributing Author: Gina Hagler These five biotechnology companies in Maryland may make history in 2021 because they have multiple therapeutic programs in trials for a variety of genetic diseases. #1 REGENXBIO is a publicly-traded company that develops products for one-and-done, single-dose solutions addressing genetic defects. Their products use adeno associated virus (AAV) viral vectors that…

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The Berlin Patient’s Success Produces A Flurry of Activity

The Berlin Patient’s Success Produces A Flurry of Activity

The Berlin Patient’s success provided optimism that there was a way to permanently disable HIV and eradicate it from an infected person.  While a bone marrow transplant is not appropriate for most HIV patients, what we have learned from his experience has provided us clues to find a cure.  Removing the door handle HIV uses…

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The Race for a COVID Vaccine Foreshadows a Medical Revolution

The Race for a COVID Vaccine Foreshadows a Medical Revolution

Contributing Author Luke Williams, Sales and Marketing  Conventional vaccine development can take many years, yet vaccines targeting the novel coronavirus were approved and began distribution in under 12 months. Pfizer, Moderna, and AstraZeneca have led the race, announcing promising interim results in their vaccine trials, with Pfizer’s and Moderna’s vaccines showing upwards of 90% effectiveness.…

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The History of HIV Cure Research: Reaching for a Cure

The History of HIV Cure Research: Reaching for a Cure

Contributing Author: Gina Hagler A new immune deficiency illness came on the scene in 1981. In the years immediately following, four questions arose that indicated the uncertainty of the time: What was this illness? How was it transmitted? Could it be treated? Could it be cured? By 2004, when the number of people living with what…

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The History of HIV Cure Research: The Latest Research in BioPharma

The History of HIV Cure Research: The Latest Research in BioPharma

Contributing Author: Gina Hagler In the forty years since the HIV/AIDS pandemic began in 1981, researchers have learned a lot about this disease that destroys the immune system. Early on, they identified the method of transmission and the means of HIV replication. They went on to successfully turn what had been a deadly disease into a…

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ARC of HIV History 2 – A Beginning and an End

ARC of HIV History 2 – A Beginning and an End

Contributing Author John Vandermosten, Senior Biotechnology Analyst This is the second installment of our series on the Arc of HIV History which examines the earliest emergence of HIV and the progress that has been made until today.  In Part 2 we look at the genesis of the first approved HIV drug and the first cure of…

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List of 88 Gene Therapies

List of 88 Gene Therapies

Contributing Author Luke Williams, Sales and Marketing  Biotechnology is a rapidly expanding sector where game-changing innovation is a daily occurrence. Gene and cell therapies are of particular interest because of the steep technology curve driving the technology platform. The gene and cell therapy industry is characterized by numerous small, competitive, agile businesses; each with a…

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In Memory of Timothy Ray Brown

In memory of Timothy Ray Brown

Contributing Author : Jeff Galvin, CEO and Founder American Gene Technologies A Message From the CEO of American Gene Technologies® Timothy Ray Brown – March 11, 1966 – September 29, 2020 Timothy Ray Brown was both a person and a turning point in the arc of HIV history. Timothy received a bone marrow transplant and…

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4 Global Trends That Will Affect ​HIV Cure​ Research in 2025

4 Global Trends That Will Affect ​HIV Cure​ Research in 2025

Contributing Author: Gina Hagler Researchers have been working on an HIV Cure since the first reports of the illness appeared in 1981. We now have effective treatment in the form of a cocktail of antiretroviral drugs that stop the HIV virus’s progression to full-blown AIDS, but It is not a cure. Despite their benefits, antiretrovirals…

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The Arc of HIV History

The Arc of HIV History

Contributing Author John Vandermosten, Senior Biotechnology Analyst The Early Days When We Knew Nothing It is uncertain how the human immunodeficiency virus or HIV initially infected humans although there are educated guesses.  Research has suggested that the virus crossed species from chimpanzees to humans in Africa early in the 20th century.  Hunters would target chimpanzees or…

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