Claims Scope:

Patent Issued November 5, 2021. 

 

Sequence-specific guide+ backbone 

• 90% identity to SIN 31 (CCR5, Vif at Tat) (Gd+Bb) 
• 90% identity to SIN 1, 2, & 108 (mir30 CCR5, mir21 Vif, and mir185 Tat, any order) (Gd+Bb) 

 

Claims Overview Seq ID No 31 

– lentiviral vector (claim 1, 13)  

– lentiviral particle (claim 3, 16)  

– modified T Cell (claim 6) 

– method of producing PBMC (claim 9)  

Claims Overview Seq Id Nos 1, 2 & 108 

– lentiviral vector (claim 13) 

– lentiviral particle (claim 16)  

– modified T Cell (claim 20) 

– method of producing PBMC (claim 23)