Immunotherapy, No Pre-Immunization, HIV(+) Patients JP

Country:
Japan

Docket No:
436313-001510

Publication Number:
2020-515234

Patent Expiry:
01/09/2038

Claims Scope:

Patent issued April 10, 2023. 

 

Sequence-specific Method of Manufacture and Composition Use (treatment) Claims 

 

– method of producing transduced PBMS (claim 1)  

– composition for treating HIV infection (claim 16) 

 

– sequence specific limitations include: 

  1. 90% SEQ ID NO 31: CCR5, Vif and Tat (microRNA backbone plus guide, in order) 
  1. 90% SEQ ID NO: 97, 6 and 7 (CCR5, Vif and Tat guide, any order)  

 

*note no claims to SEQ ID NOS 1, 2 and 3/108 (CCR5, Vif and Tat backbone plus guide)